Syrian Rue Peganum Harmala – Seeds


Syrian rue, Peganum harmala, is a plant that since old times is used to increase the effects of psychedelic substances. Peganum Harmala is a Mao inibitor. The Syrian Rue Seeds can be chewed or can be ground and mixed in a drink. Syrian rue is often planted close to buildings to keep out the “Evil Eye”.

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Contains 10 grams Syrian Rue (Peganum harmala) seeds. In sealed packaging.

Effects of Syrian Rue

Syrian Rue is mainly used as an MAOi and is most commonly used in tandem with other plants and substances containing DMT. Nonetheless, the seeds have some standalone effects, too. Syrian Rue is said to have some characteristics of antidepressants. It is also said to stimulate the imagination. Some psychonauts are experimenting with high doses of Syrian Rue to induce a trip.

The effects:

  • Relaxing
  • Clear mind
  • Aphrodesiac
  • Hallucinations , in a higher dose
  • Dream-like state, in a higher dose

Syrian Rue as an MAO – inhibitor

The seeds of Syrian Rue (Peganum harmala) contain the alkaloid harmaline. Harmaline works as MAO inhibitor (MAOi, or Monoamine Oxidase inhibitor). Monoamine oxidase (MAO) is an enzyme that naturally occurs in our bodies. This enzyme breaks down neurotransmitters such as serotonin, norepinephrine and dopamine, but also psychoactive substances such as psilocybin, N,N-DMT and 5-MeO-DMT.

Your body usually doesn’t absorb these substances when you consume them orally. Syrian Rue temporarily inhibits MAO, preventing your body from taking down these substances. This means that you can take substances like DMT orally when combined with Syrian Rue.

Owing to its status as MAOi, Syrian Rue is often used as an ingredient for anahuasca or ayahuasca analog, as a replacement of Banisteriopsis Caapi. Anahuasca is a drink that mimics the effects of ayahuasca with an alternative composition and preparation. Many people prefer Syrian Rue over Caapi because the seeds are easier to prepare and the bodily effects (stomach aches, nausea, vomiting) are much less intense.

Use of Syrian Rue

It is commonly agreed that 3 grams of Syrian Rue is a sufficient dose when using it as an MAOi. Take the seeds about 15 to 60 minutes before consuming the other psychoactive substance. The effects of Syrian Rue last approximately 3 to 4 hours.

To get the stand alone effects of Syrian rue, 20 grams can be used.

There are different methods of consuming Syrian Rue seeds. In principle, it’s possible to eat the Syrian Rue seeds.

You can take the seeds orally, carefully chewing them about 30 seconds before swallowing them. You can also pulverize the seeds with a mortar and pestle and use the powder to fill gel capsules.

You can also choose to create a hot water infusion with Syrian Rue seeds. This method is slightly lighter on the stomach. Use approximately 3-4 grams of Syrian Rue seeds with 200 ml of water and 50 ml of lemon juice. Finely grind the seeds and let the powder simmer in water for about 30 minutes. Then sieve the tea and drink it. Instead of water us wine to make a intoxicating drink, called Harmala wine


There are risks associated with the use of Syrian Rue. The substance tyramine is also not broken down by your body after using a MAOi. When tyramine accumulates in your blood this can increase your blood pressure enormously (hypertension) up to dangerous levels. To prevent this from happening you must therefore ensure that you have as little as possible of tyramine in your food and drinks. It is strongly recommended to do a “MAO diet” at least 12 hours prior to the intake of Peganum harmala.

Click here for a list of foods and drinks to avoid during your MAO diet.

Click here for a list of medicines and drugs that should never be used in conjunction with Peganum harmala.

Cultivation of Syrian Rue

Syrian Rue is rather notorious for being difficult to cultivate. It’s a perennial plant that is found in warm, fairly dry parts of Southern Europe, the Middle East and South Asia. The plant is not so suitable for cultivation in the mild sea climate of Western Europe, but it’s possible if you grow it inside.

  1. Sow the seeds in late spring in a mixture of soil and plenty of sand. Be wary of overwatering.
  2. Place the pot in a sunny spot and make sure the temperature exceeds 20°C at all times.
  3. After a few weeks, the seeds should germinate and if it’s warm enough you can move the pot outside.

History of Syrian Rue

Syrian Rue (Peganum Harmala) belongs to the family Nitrariaceae. It originates from warm, rather dry areas, being found from the Mediterranean and the Middle East all the way to India, Pakistan and even China.

Syrian Rue has a very rich and ancient history. The plant is often linked to two legendary magical herbs: soma and moly. Soma was a herbal drink that in ancient Persia served as medicine and panacea. The identity of this magical drink is a historical mystery, but many scholars suspect that the psychoactive plant Syrian Rue could have been its main ingredient. Moly is a magical herb that figures in the Greek myths of the Odyssey. The god Hermes provides the hero Odysseus with moly to protect him from the witchcraft of the sorceress Circe. Historians aren’t sure which herb the Greeks were referring to with moly, but its description (a white flower with black roots) is reminiscent of Syrian Rue.

Syrian Rue is part of rituals and folk medicine almost everywhere where it can naturally be found. In India and Pakistan, the plant has many gynecological uses. It serves as a treatment for menstruation pains, to alleviate the discomforts of labor and as an aphrodisiac. In Iran and Iraq, Syrian Rue seeds are thrown into fires to ward off evil spirits. In North Africa, the smoke of Syrian Rue is inhaled as a cure for headaches, venereal diseases, and as a way to expel the “evil eye”.


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